The first cruise ship of the season will roll into St. George's this weekend with more than 450 passengers.
The Deutschland will sail through Town Cut on Sunday morning and come alongside for 10 hours before she heads off to the Azores.
The town's mayor Kenny Bascome told the Bermuda Sun he was expecting a "very profitable season".
He added: "We are working with what we have been dealt with.
"My feelings are if you have a positive outlook things will work out in a positive way.
"I have spoken to the business people in the town and most of them will be open for business this weekend.
"The Parks Department has promised me that they will cleaning up Tobacco Bay.
"The cafe will not be open but by the time the Veendam cruise ship comes in later in the month we are hopeful it will be.
"We're still working at getting everything up and running for the cruises."
The Corporation of St. George's will be holding a public meeting on April 22 to make sure everything is in place for the first arrival of the Veendam.
The cruise ship will make 24 trips to Bermuda in 2010 and although she will not dock in St. George's she will anchor out at Murray's Anchorage and passengers will be ferried into the town.
The Veendam will bring in more than 1,300 passengers from New York on each voyage.
Mr. Bascome said: "I expect that we will lose around six of the 24 trips due to bad weather as the ship will just carry on to Hamilton.
"But I hope the government will lay on extra shuttle buses and ferries to get those folks up to St. George's.
"There is a new enthusiasm in St. George's right now and everyone is determined to make the best of the situation.
"The fact that passengers from the Veendam are being ferried into St. George's should be great news for the businesses of the town."
This Saturday a family fun day with bouncy castles and majorettes will take place in The Square.
And on April 10 residents will band together to take part in a community clean-up to pick up debris and litter from hedges and road sides.